Antibacterial substances related to pantothenic acid

Microbic Decomposition of Pantothenic Acid.

The metabolism of pantothenic acid.

The formulation of this pathway was based on: (a) the finding that cysteine supplies the sulfur-containing moiety of CoA (3,4); (b) the activities of pantetheine and pantothenylcysteine as growth factors for Acetobacter suboxydans (4-6) and Lactobacillus helveticus (7); (c) the presence of enzymes in these two organisms and also in Lactobacillus bulgur&s which decarboxylate pantothenylcysteine ...

The Structure of Cyameluric Acid, Hydromelonic Acid and Related Substances.

Over a century ago, in 1835, Leopold Gmelin' prepared the substance tripotassium hydromelonate by heating potassium ferrocyanide with sulfur; he also made other salts of hydromelonic acid, and carried out analyses, which, however, were not sufficiently accurate to lead to correct formulas. He recognized the similarity of the substances to the group of nitrogen compounds discovered and named by ...

Antibacterial Substances Separated from Plants.

Interest is arising in the possible use of higher plants as the source of naturally occurring antibiotic substances. The use of higher plants in the treatment of disease is as old as the art of healing itself. Isaiah of Biblical times suggested that a plaster of figs be placed on boils as a treatment of this form of infection. Hyssop and cedarwood were used in the cleansing of lepers. The Orien...

The availability to the chick of pantothenic acid in foods.

1. The content of total pantothenic acid (PaA) in two foodstuffs of microbial origin was measured by standard microbiological and chick biological assays. 2. Substantially and consistently higher values were found by the chick assay than by the microbiological determination, indicating that PaA-containing compounds were present that were not utilized by the test micro-organisms but were availab...